Codeine could enrich the neuromuscular blocking motion of skeletal muscle mass relaxants and develop an increased degree of respiratory melancholy.

Postmarketing circumstances of respiratory melancholy, such as fatalities, are actually noted with utilization of promethazine in pediatric sufferers. Concomitant administration with other respiratory depressants may possibly increase the chance of respiratory melancholy.

Never flush prescription drugs down the bathroom or pour them into a drain Except instructed to take action. Adequately discard this item when it truly is expired or no more necessary. Consult your pharmacist or regional squander disposal company.

question your health care provider in regards to the Risk-free usage of Liquor if you are using this medication. Liquor might make the side effects of promethazine worse.

Make certain you know the way to choose this product or service and what other medicines it is best to avoid getting with it. See also Drug Interactions part. Get medical help straight away if any of those very major Unintended effects occur: slow/shallow respiration, uncommon lightheadedness, extreme drowsiness/dizziness, issue waking up.

We foresee reposting the photographs when we're capable recognize and filter out photos that don't match the information presented from the drug labels. NDC Codes

The effects of concomitant use or discontinuation of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with codeine are complex.

Codeine (3-methylmorphine) is analogous to morphine, but a methyl group is substituted with the hydroxyl team around the variety 3 carbon of the morphine molecule. Codeine is an agonist with the three typical opioid receptors (Mu, delta, and kappa). Even now, it's 20 instances more affinity for that mu receptor when put next to your delta and possesses considerably significantly less selectivity for that kappa receptor.

Employing this medication with any of the next medicines is not recommended. Your doctor might make your mind up not to treat you using this type of medication or adjust a few of the other medicines you're taking.

Postmarketing circumstances of respiratory despair, such as fatalities happen to be documented with use of promethazine in pediatric individuals.

The dose of this medicine are going to be diverse for various clients. Adhere to your health practitioner's orders or the directions on the label. The following information involves only the typical doses of this medication. Should your dose is different, do not transform it Except if your doctor tells you to take action.

Codeine produces peripheral vasodilation which may cause orthostatic hypotension or syncope. Manifestations of histamine release and/or peripheral vasodilation may perhaps incorporate pruritus, flushing, crimson eyes and perspiring and/or orthostatic hypotension.

Some side effects could come about that usually do not need to have clinical attention. These Uncomfortable side effects could disappear throughout treatment method as Your whole body adjusts to your medication. Also, your wellness care Specialist might be able to tell you about approaches to forestall or lessen Many of these Unintended effects.

Youngsters really should be supervised for the duration Promethazine codeine syrup of bicycle Driving and also other perhaps dangerous activities to avoid injuries. Limit alcoholic beverages. Discuss with your health care provider In case you are employing cannabis (cannabis).